منابع مشابه
Biomarkers of primary open-angle glaucoma.
Primary open-angle glaucoma (POAG) is a primary neuronal disease of the optic nerve without a definable cause, and is often associated with increased intraocular pressure. Worldwide, POAG is the second leading cause of blindness; there are 45 million people today with POAG and bilateral blindness is present in 4.5 million of these. In order to elucidate the possible etiologic factors in POAG, w...
متن کاملBiomarkers in primary open angle glaucoma
Glaucoma, a leading cause of blindness worldwide, is currently defi ned as a disturbance of the structural or functional integrity of the optic nerve that causes characteristic atrophic changes in the optic nerve, which may lead to specifi c visual fi eld defects over time. This disturbance usually can be arrested or diminished by adequate lowering of intraocular pressure (IOP). Glaucoma can be...
متن کامل[Impact of biomarkers in primary open-angle glaucoma].
EDITORIAL What is a biological marker? According to the Spanish Language Royal Academy, it is any easily detectable atom or substance which allows for the identification of physical, chemical or biological processes. In biomedicine we refer to biological markers as the molecules we are able to determine in bodily tissues and fluids by means of lab techniques and which, according to their charac...
متن کاملPrimary open-angle glaucoma
Primary open-angle glaucoma (POAG) is an idiopathic disorder in which the resistance to outflow through the trabecular meshwork gradually increases and the intraocular pressure (IOP) rises, causing irreversible damage to the optic nerve POAG is the second most common cause of vision loss in the U.S. Usually asymptomatic until advanced visual field loss has occurred; less than 50% of those...
متن کاملCytokine biomarkers in tear film for primary open-angle glaucoma
PURPOSE To determine the utility of tear film cytokines as biomarkers for early primary open-angle glaucoma (POAG). METHODS Patients without POAG and eye drop-naïve patients with newly diagnosed POAG were recruited from an academic hospital-based glaucoma practice. Tear films of recruited patients were obtained and analyzed using a multiplex, high-sensitivity electrochemiluminescent enzyme-li...
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ژورنال
عنوان ژورنال: Expert Review of Ophthalmology
سال: 2010
ISSN: 1746-9899,1746-9902
DOI: 10.1586/eop.10.73